A New Graph-Transformer Framework for EEG-Based Differentiation of Alzheimer’s Disease and Frontotemporal Dementia

Published in Journal of Neural Engineering, 2024

This research presents a novel graph-based transformer architecture that integrates spatial-temporal EEG features for the classification of Alzheimer’s Disease and Frontotemporal Dementia. The work demonstrates state-of-the-art performance in biomedical signal processing applications.

Model Architecture

Model Architecture Graph-based transformer architecture integrating spatial–temporal EEG features

Key Achievements

MetricResult
Accuracy99.1%
vs. SOTA+7-18 percentage points
  • Designed and implemented a novel graph-based transformer integrating spatial–temporal EEG features
  • Built an end-to-end processing pipeline and benchmarked classical ML vs. deep learning approaches
  • Led a multi-team project, owning the full EEG classification pipeline

EEG Feature Analysis

EEG Heatmap Power spectral density heatmap comparison showing brain activity differences

Research Details

Role: First author — responsible for design, analysis, and drafting

Code Repository: github.com/yosftag1/eeg-alzheimer-classification

Status: Under Review at IOP Journal of Neural Engineering

Timeline: September 2023 – June 2024 (Bachelor’s Thesis Project)

Preprint: Available upon request

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